Supplementary Materialsmolecules-21-00368-s001. enzyme, the addition of the 21-hydroxypregnane-20-one moiety to a

Supplementary Materialsmolecules-21-00368-s001. enzyme, the addition of the 21-hydroxypregnane-20-one moiety to a 3-substituted steroid is certainly harmful for G6PDH inhibition. The species-specificity of specific steroid derivatives towards parasite G6PDH and the corresponding biochemically validated binding models disclosed in this work may prove useful for the development of selective inhibitors against the pathogens enzyme. and encompass parasite… Continue reading Supplementary Materialsmolecules-21-00368-s001. enzyme, the addition of the 21-hydroxypregnane-20-one moiety to a