Objective To test the hypothesis that chronic metformin treatment enhances insulin-induced vasodilation in skeletal muscle resistance arteries and arterioles. of endothelin-1 (ET-1) signaling created 20% dilation and removed the difference between metformin-treated and neglected OLETF rats in insulin-induced dilation of SFA. As opposed to the SFA metformin didn’t alter insulin-stimulated vasodilation in gastrocnemius give food… Continue reading Objective To test the hypothesis that chronic metformin treatment enhances insulin-induced