TRIM5 provides a cytoplasmic block to retroviral infection, and orthologs encoded by some primates are active against HIV. find that the evolutionary episodes of positive selection that have acted on and are mutually exclusive, with generally only one of these genes being positively selected in any given primate lineage. We interpret this to mean that… Continue reading TRIM5 provides a cytoplasmic block to retroviral infection, and orthologs encoded