Multipurpose Prevention Technology (MPTs) are brand-new tools targeted at reducing or stopping multiple and overlapping sexual and reproductive health threats faced by females and couples around the world. to formulation and automobile or item delivery systems and consider how choices in product-related characteristics may influence future demand for delivery and use of future products. We attract on examples from your development of fresh single-purpose HIV and contraceptive products and then lengthen our discussion to the development of MPTs including vaginal rings and injections. This article is based on a demonstration in the “Product Development Workshop 2013: HIV and Multipurpose Prevention Technologies ” held in Arlington Virginia on February 21-22 2013 It forms portion of a special product to = 128 mixtures) would have been unwieldy they used statistical methods (fractional factorial orthogonal design) to reduce vaccine scenarios to eight with participants rating each of the eight scenarios on a 5-point acceptability level from “highly likely” to “highly unlikely”. Analyses of the acceptability scores enabled identification of most and least suitable vaccine scenarios overall and by group as well as the effect of individual vaccine attributes on acceptability. For example they found Ezatiostat effectiveness (95% versus 50%) to have the greatest effect on acceptability across all three groupings while variety of dosages had a substantial effect on acceptability of 1 group. In South Africa Terris-Prestholt and co-workers conducted a study with over 1000 sexually energetic females to assess demand for a variety of brand-new HIV prevention strategies including feminine condoms microbicide gel and diaphragms. The study included details on socio-demographics reproductive and intimate wellness histories and two discrete choice tests to explore how women’s choices mixed by (1) product-related qualities and (2) potential distribution and advertising strategies. In the initial experiment women had been provided six different situations IFI6 where they chose among three choices like the choice between two of the brand new prevention strategies or another choice to choose neither of the new options but to do what they did last time they had sex. (Based on a prior response to questions about the last sexual take action this Ezatiostat third option was either to “use no barrier method” or to “make use of a male condom”). Each of the three options was assigned a set of product attribute ideals including HIV prevention performance (0% for no barrier method 35 55 75 or 95% for other options) pregnancy risk reduction (0% 35 55 75 95 potential for key use (yes/no) and price (free to 20 rand or approximately $3 in 2005 for microbicides or female condoms and up to 80 rand for any reusable diaphragm). Analyses indicated women’s general preferences between the three fresh HIV prevention methods (microbicides and then diaphragm Ezatiostat was desired over woman condoms). They also recognized the impact of specific attributes on method choice; for example both HIV and pregnancy prevention effectiveness were very important to women with HIV prevention more Ezatiostat than twice as important as pregnancy prevention for women who considered themselves to be at high risk for HIV. Women who had used condoms were more likely to choose “neither of the two options” whereas women who chose one of the two new prevention methods were more likely to be living with a partner or Ezatiostat to have had problems getting a partner to use a condom. Women who reported prior problems with male condom use were also more likely to endorse “secret use” as an important product attribute (Terris-Prestholt et al. 2008 3 Discussion We presented several approaches to assessing acceptability and its underlying determinants (perceptibility attitudes and understanding of product characteristics partner dynamics service delivery contexts) during early item advancement and provided types of how these details might inform marketing of the items’ physicochemical properties determine and characterize populations most or least more likely to demand services and consider the implications of item advancement decisions on additional clinical tests and item introduction. Study to see the look of new MPTs for increased adherence and acceptability act like the.